Human IL-12 GENLISA™ ELISA

Introduction: Interleukin-12, abbreviated IL-12, is a cytokine that induces differentiation of naive helper T cells (Th0 cells) to Th2 cells. Upon activation by IL-12, Th2 cells subsequently produce additional IL-12. It has many biological roles, including the stimulation of activated B-cell and T-cell proliferation, and the differentiation of CD4+ T-cells into Th2 cells. It is a key regulator in humeral and adaptive immunity. IL-12 induces B-cell class switching to Ice, and upregulates MHC class II production. Overproduction of IL-12 is associated with allergies.