Introduction: Hepatitis E virus (HEV), an RNA virus of the Hepeviridae family, is an enterically transmitted, self-limiting, acute, viral hepatitis. Transmission is through large-scale waterborne epidemics and few epidemics have spread through person-to-person contact or fecally contaminated food. Vertical transmission of HEV from infected mother to fetus causes high fetal and perinatal mortality. Other means of transmission are such as zoonotic transmission, which can fluctuate depending upon the region and strain of the virus.